Cardiorespiratory recovery from apneas requires dynamic responses of brainstem circuitry.One implicated component is the raphe system of Pet1-expressing (largely serotonergic) neurons, however their precise requirement neonatally for homeostasis is unclear, yet central toward understanding newborn cardiorespiratory control and dysfunction.Here we s
Genome sequences of human cytomegalovirus strain TB40/E variants propagated in fibroblasts and epithelial cells
Abstract The advent of whole Upper Wire Harness genome sequencing has revealed that common laboratory strains of human cytomegalovirus (HCMV) have major genetic deficiencies resulting from serial passage in fibroblasts.In particular, tropism for epithelial and endothelial cells is lost due to mutations disrupting genes UL128, UL130, or UL131A, whic
Development and implementation of the international AIDA network spondylarthritis registry
During the last decade, spondyloarthritis (SpA) has increasingly been considered a disease at the crossroads between autoimmunity and autoinflammation.Some patients may even present with autoinflammatory-related manifestations, including fever, hidradenitis suppurativa, other neutrophilic dermatoses, and an unusually high increase in inflammatory m
User Authentication Mechanisms Based on Immersive Technologies: A Systematic Review
Immersive technologies are revolutionary technological advancements that offer users unparalleled experiences of immersion in a virtual or mixed world of virtual and real elements.In such technology, user privacy, security, and anonymity are paramount, as users often share private and sensitive information.Therefore, user authentication is a critic
Re-Examination of the Decadal Change in the Relationship between the East Asian Summer Monsoon and Indian Ocean SST
This study examines the decadal change in the relationship between two major Indian Ocean (IO) sea surface temperature patterns, namely the Indian Ocean dipole (IOD) and northern IO and the East Asia summer monsoon (EASM) in the early 2000s.In 1991–1999, the former epoch, the interannual Upper Wire Harness variability of EASM was associated w